North American Pediatric Aplastic Anemia Consortium (NAPAAC)
The North American Pediatric Aplastic Anemia Consortium (NAPAAC) is a collaborative research effort that seeks to develop better therapies for children with aplastic anemia by combining the expertise and resources of the leading pediatric hematologists in North America.
In children, aplastic anemia is most often the result of an inappropriate immune system attack on the bone marrow. However, some children with low blood cell counts may have an underlying genetic predisposition that leads to bone marrow failure. Hence, NAPAAC researchers are also actively studying such inherited bone marrow failure syndromes (IBMFS). Furthermore, because aplastic anemia can be difficult to distinguish from a condition of Myelodysplatic Syndrome (MDS) and can also lead to the development of MDS, NAPAAC also seeks to better understand MDS in children.